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Retinal Nerve Fiber Layer Thickness in early-stage Diabetic Retinopathy with Vitamin D deficiency

Session Details

Session Title: Vascular Diseases and Diabetic Retinopathy III

Session Date/Time: Saturday 19/09/2015 | 16:30-18:00

Paper Time: 17:10

Venue: Clio

First Author: : O.Ateş TURKEY

Co Author(s): :    A. GUNGOR   H. BILEN           

Abstract Details

PURPOSE:To evaluate retinal nerve fiber layer (RNFL) thickness in early stage DRP patients with vitamin D deficiency (VDD) and a early stage DRP patients without VDD

Setting:

This study made a comparison of 50 patients with early-stage DR with VDD (group 1) and 50 patients with early stage DR without VDD (group 2).

Methods:

All patients were examinated by same Ophthalmolog. Mean RNFL thickness thickness were determined by OCT. The same ophthalmologist performed the OCT imaging in all subjects. Vitamin D levels were measured by using a radioimmunoassay in all patients. VDD was defined, in accordance with the general standards, as having 25(OH)D levels less than 20 ng/ml

Results:

There was no significant difference between the groups in terms of age and sex distribution (p>0.05). The mean serum 25(OH)D concentration of group 1 was significantly lower than in group 2 (p<0.001). The mean RNFL thickness of group 1 was significantly thinner than that of group 2 (p < 0.001). A significant relationship between the mean RNFL thickness and serum 25(OH)D concentrations was observed in group 1 (p < 0.001)

Conclusions:

İt demonstrated that vitamin D functioned as a neuroprotective component for optic nerves. Low serum 25(OH)D concentrations contribute to RNLF thinning in early stage DRP patients with VDD.

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