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Tomographic analysis of retinal nerve fiber and ganglion cell layers after epiretinal membrane surgery

Poster Details

First Author: Y.Totan TURKEY

Co Author(s):    E. Güler   A. Yüce   F.B. Gürağaç   A. Tenlik         0   0 0   0 0   0 0   0 0

Abstract Details


To evaluate the postoperative ganglion cell-inner plexiform layer (GC-IPL) and retinal nerve fiber layer (RNFL) thickness changes in eyes undergoing Brilliant Blue G (BBG) assisted epiretinal membrane (ERM) surgery using spectral-domain optical coherence tomography (OCT).


Turgut Özal University Medical Faculty Department of Ophthalmology


The study included 25 eyes of 25 patients undergoing ERM and ILM peeling using BBG. Quantitative analysis of the GC-IPL and peripapillary RNFL was performed by Cirrus HD-OCT (Carl Zeiss Meditec) preoperatively and for 6 months postoperatively on both eyes.


The mean preoperative GC-IPL (50.75 ± 24.33 µm) was significantly (p< 0.05) thinner in vitrectomized eyes compared to the fellow eyes (69.81 ± 19.09 µm), whereas the mean preoperative RNFL thickness was not significantly (p> 0.05) different between the study (91.44 ± 12.32 µm) and control eyes (89.20 ± 14.32 µm). The mean postoperative GC-IPL thickness (44.58 ± 18.57 µm) was not significantly different (p> 0.05) compared to the mean preoperative measurement (50.75 ± 24.33 µm) except for the significant reduction in inferotemporal quadrant (P< 0.05). The mean postoperative RNFL thickness (74.45 ± 11.02 µm) was not significantly different (p> 0.05) compared to the mean preoperative measurement (91.44 ± 12.32 µm) except for the significant reduction in temporal quadrant (P< 0.05).


GC-IPL and RNFL thicknesses showed localized reduction after ERM surgery with BBG during 6-month follow-up period.

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