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High intraocular pressure in 4 vitrectomized eyes with intravitreal C3F8 without high altitude travel

Poster Details

First Author: K.Brosh ISRAEL

Co Author(s):    I. Strassman   M. Seelenfreund               0   0 0   0 0   0 0   0 0

Abstract Details


: it is well known that altitude ascent with intravitreal gas can cause expansion of gas and IOP elevation1-6. According to Boyle's law the gas bubble will not expand unless a higher altitude than the gas insertion site has been reached. We report four cases in which intravitreal gas was injected at an altitude of 790m (Jerusalem). All four cases developed high IOP even though they did not reach a higher altitude in their post-operative period.


Retrospective reports of four cases


Retrospective reports of four cases are presented. Clinic files of all the cases were reviewed in addition to hospitalization data and ophthalmic emergency room files. Pars plana vitrectomy was performed in all the cases with addition of a fluid-gas exchange with 12% mixture of perfluoropropane and air. All the operations were performed at Shaare Zedek Medical Center Hospital in Jerusalem and follow up exams were at the Hospital ophthalmic outpatient clinic.


A report of four patients following vitrectomy with 12% mixture of perfluoropropane and air are presented. All four patients arrived with ocular pain following the ascent by car of 765-1100 meters to Jerusalem where the vitrectomy and gas insertion was conducted. Upon examination, all four patients had high intra ocular pressure (30-55 mmHg). Intra ocular pressure was well controlled with IOP lowering medications. None of the patients suffered from long term complications.


Caution should be taken with altitude changes in patients with intravitreal gas even if there was no ascent from the altitude in which the vitrectomy was performed.

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