First Author: Y.A.Yilmaz TURKEY
Co Author(s): G. Kaya 0 0 0 0 0 0 0 0 0
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To evaluate macular retinal thickness in diabetic retinopathy using optical coherence tomography (OCT) as an objective and noninvasive tool. The relationship between retinal thickness and standard methods of evaluating macular edema was investigated.
Sultanbeyli State Hospital , Department of ophthalmology
: 78 patients in different stages of diabetic retinopathy were examined with OCT. In addition, fluorescein angiograms as well as standard eye examinations were conducted. The control group consisted of 50 individuals with a normal macula.
In the controls, retinal thickness was 161 ± 20 μm in the fovea, 251 ± 18 μm in the temporal parafoveal region, and 271 ± 15 μm in the nasal parafoveal region. In diabetic patients, retinal thickness was increased to 312 ± 126 μm in the fovea, 344 ± 79 μm in the temporal retina, and 365 ± 105 μm in the nasal retina, respectively. The differences between diabetics and controls were highly significant (P < 0.002). Retinal thickening correlated with fluorescein leakage in the angiograms to some extent. There was an intermediate correlation between retinal thickness and visual acuity, particularly in patients without macular ischemia. Sensitivity of detecting clinically significant macular edema by measuring foveal retinal thickness was 77% and specificity was 91%.
Optical coherence tomography allows us to quantify retinal thickness in diabetic retinopathy with excellent reproducibility. OCT is able to detect sight-threatening macular edema with great reliability.