First Author: C.Traversi ITALY
Co Author(s): G. Martone E. Nuti P. Pichierri E. Latronico 0 0 0 0 0 0 0 0 0
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To analyse the effect of combined grid laser photocoagulation combined with anti-vascular endothelial growth (anti-VEGF) factor agents treatment on macular thickness (MT) subfoveal choroidal thickness (SFCT) of diabetic macular edema (DME) patients.
Ophthalmology Department, University of Siena, Italy
16 eyes with DME were examined before and after macular grid laser photocoagulation and three anti-VEGF injections. The mean MT and SFCT was measured using spectral domain ocular coherence tomography (SD-OCT) with ehanced depth imaging protocol.
All the eyes showed a significant reduction on MT (p=.004) and on SFCT (p=.02) after combined treatment. The relationship between the choroidal and macular thicknesses was no evident.
Eyes with DME treated with grid laser photocoagulation and anti-VEGF agents showed a reduction of MT and SFCT. The reduction of choroidal thinning might be related to the improvment of diabetic retinal tissue hypoxia.