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Correlation between external layers integrity by optical coherence tomography and visual prognosis in diabetic macular edema

Poster Details

First Author: A.Soler-Garcia SPAIN

Co Author(s):    A. Gonzalez-Gomez   J.M. Sandoval               0   0 0   0 0   0 0   0 0

Abstract Details


To evaluate the visual outcome in patients with diabetic macular edema after antiangiogenic treatment based on the integrity of the external limiting membrane and IS / OS layer using OCT


Hospital Universitario Virgen de la Victoria, Málaga (Spain)


We studied 4 clinical cases of patients with diabetic macular edema treated with Ranibizumab evaluating the integrity of the external limiting membrane and IS/OS layer after resolution of edema. we measured the best-corrected visual acuity in these patients. The intraocular pressure was normal and none of these patients showed other associated diseases to justify a worse visual acuity.


the results showed that the patients who had a loss of integrity of these layers manifest worse visual acuity than those in which they were maintained. These changes were sustained over time. 2 patients showed integrity of these layers, and the 1-year follow visual acuity was maintained above 0.7 (Snellen) regardless of the number of injections required.


Advances in visualization of retinal anatomy by OCT with new equipment allows us an accurately assess of the retinal layers. We know that the retinal thickness in the acute phase of diabetic macular edema relates poorly with the final visual outcome. The integrity of the outer layers as shown by recent studies can determine the visual prognosis and treatment response.

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