First Author: Y.B.Sakalar TURKEY
Co Author(s): T. Yilmaz A. Yilmaz A.A. Karci D. Esen 0 0 0 0 0 0 0 0 0
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To evaluate short-term changes in findings of optical coherence tomography after intravitreal dexamethasone implant in patients with retinal vein occlusion.
Prospective uncontrolled study
Thirty eyes of thirty patients (18 males and 12 females) treated with intravitreal 0.7 mg dexamethasone implant due to retinal vein occlusion were included to the study. The best corrected visual acuity, intraocular pressure, axial length were measured at baseline. The subfoveal choroidal thickness and central foveal thickness were measured by optical coherence tomography. The measurements were repeated at the first week and 1, 2, 3 months, postoperatively.
Mean age of patients was 62.83 ± 9.65 years (range 44 to 83 years). Mean axial length was 22.65 ± 0.79 mm. The mean subfoveal choroidal thickness was 336.3 ± 45.37, 331.53 ± 43.65, 326.13 ± 42.85, 325.9 ± 41.88 and 325.87 ± 40.3 µm at baseline, first week, first month, 2 months, and 3 months, respectively. There was no significantly difference between subfoveal choroidal thickness at baseline and first week (p = 0.68) but subfoveal choroidal thickness was significantly lower when compared with the baseline measurement (p < 0.05). The mean central foveal thickness was 528±201.64 at baseline and 476.13±181.70, 425.7±171.54, 394,7±172.3 and 376.23±171.61 µm at follow-ups. Baseline central foveal thickness was significantly thicker than follow-up measurements (p < 0.05). IOP was significantly higher 1 and 3 months when compared with baseline (p < 0.05). Visual acuity improved significantly at follow-ups (p < 0.05).
Our results revealed that in short-term, both subfoveal choroidal thickness and central foveal thickness were decreased after treatment of 0.7 mg dexamethasone implant in patients with retinal vein occlusion.