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Correlation between structural changes and visual acuity in diabetic macular edema

Poster Details

First Author: F.Rosales Villalobos SPAIN

Co Author(s):    I.M. Baquero Aranda   J.M. Sandoval Codoni               0   0 0   0 0   0 0   0 0

Abstract Details


To relate retinal morphological changes studied by light optical coherence tomography with visual function in diabetic macular edema.


A retrospective observational study was performed on 64 eyes of 45 patients with diabetic macular edema untreated. In none of them was detected in macular ischemia in fluorescein angiography.


The mean age was 65.2 years. All patients underwent complete ophthalmic examination and optical coherence tomography (Cirrus OCT). Classifying the type of edema or cystic sponge with the presence or absence of serous neuroepithelium, macular thickness, or no disruption of the junction between external and internal segments of the photoreceptors and the outer limiting membrane was analyzed. We correlate these data with the logarithm of the minimum angle of visual resolution. Student t test was used, pearson coefficient and linear regression for statistical analysis.


It was observed that patients with cystoid macular edema had lower visual acuity in patients with edema sponge (logMAR 0.62 + / -0.39 logMAR and 0.41 + / -0.22), as well as greater macular thickness decreased visual acuity. The presence of a disruption in the outer limiting membrane (logMAR 0.89 + / -0.37) or at the junction between external and internal segments of the photoreceptor (logMAR 0.87 + / -0.34) is associated with a visual acuity less than the integrity of these structures. No statistically significant relationship between visual acuity and serous detachment of neuroepithelium was found.


The optical optical coherence tomography demonstrated that disruption of the external limiting membrane and the junction between the outer and inner segments of photoreceptors is strongly associated with decreased visual acuity in diabetic macular edema. Optical coherence tomography is essential in the study of diabetic macular edema, this test correlates structural and functional findings. It is useful to establish treatment guidelines and visual prognosis.

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