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Spectral domain optical coherence tomography (SD-OCT) predictors of visual outcome in patients with macular oedema (MO) due to branch retinal vein occlusion (BRVO) treated with intravitreal ranibizumab injections

Poster Details

First Author: S.Mukherjee INDIA

Co Author(s):    R. Roy   D. Das               0   0 0   0 0   0 0   0 0

Abstract Details


To correlate the final visual outcome in patients of Branch Retinal Vein Occlusion (BRVO) with Macular Oedema (MO), with the structural integrity of the macula as analysed by SD-OCT at presentation.


Sankara Nethralaya, Kolkata, a tertiary eye care centre in eastern India.


Retrospective analysis of 74 eyes of 74 patients with perfused MO secondary to BRVO, who had not received any previous treatment, were done. All patients had been subjected to OCT evaluation and Ranibizumab injection, monthly, for 3 months. Thereafter patients were evaluated monthly with best corrected visual acuity (BCVA), OCT and fundus examination and treated with Ranibizumab injection on a pro-re-nata (PRN) basis.


Mean duration of follow up was 204.69 ± 186.58 days. Mean BCVA, in logarithm of the Minimum Angle of Resolution (logMAR), improved from 0.54 ± 0.34 to 0.37 ± 0.34 (p<0.001). Mean Central macular thickness improved from 525.36 ± 173.34 µm to 302.42 ± 140.70 µm (p<0.001). Multivariate analysis revealed integrity of the External limiting membrane (ELM) and inner segment-outer segment (IS-OS) junction as the most important predictor of a good visual outcome (p<0.001) whereas presence of neuro-sensory detachment and cystic spaces had statistically insignificant effect on the final visual outcome.


Integrity of ELM and IS-OS junction at presentation were found to be the most important factors in predicting a good visual outcome.

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