First Author: N.Kir TURKEY
Co Author(s): Z. Cebeci B. Tanyildiz 0 0 0 0 0 0 0 0 0
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To determine the results of indocynanine green angiography (ICGA) guided half fluence photodynamic theraphy (PDT) in patients with chronic central serous chorioretinopathy (CSC).
A retrospective chart review included 20 eyes of 19 patients with chronic CSC and continuing symptoms for at least 6 months duration. ICGA was used to confirm choroidal vascular dilatation and hyperpermeability . ICGA guided half fluence ( 25 j/cm2 for 83 s ) PDT was performed to choroidal hypermeability areas. Changes in best corrected visual acuity (BCVA), central foveal thickness (CFT) and subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging spectral domain optical coherence tomography (EDI OCT) , recurrence rates and complications were evaluated.
The study included 11 (%57.9) men and 8 (%42.1) women with mean age of 47.35 ± 9.03 years (range 32-61) . Mean follow-up time was 9.9 months (range 4-24). The mean BCVA improved significantly from 0.45 ± 0.25 LogMAR at baseline to 0.18 ± 0.35 at the last visit (p<0.05) . The pretreatment mean CFT was 338.35 ± 86.5 µm and declined to 172.65 ± 31.6 µm at the last follow-up (p<0.05). Baseline mean SFCT decreased significantly from 381.10 ± 87.60 µm to 277.8 ± 73.07 µm at the end of follow-up (p<0.05). One eye developed choroidal neovascularization 2 months after PDT and treated with intravitreal bevacizumab.
Photodynamic therapy resulted both anatomic and visual success in half fluence rates. ICGA guided half fluence PDT was effective in the treatment of chronic central serous chorioretinopathy.