First Author: D.Karagiannis GREECE
Co Author(s): G. Kontadakis N. Klados I. Tsoumpris A. Kandarakis E. Parikakis M. Tsilimbaris 0 0 0 0 0 0 0 0 0
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To investigate the existence of pseudoexfoliation syndrome (PXF) as a risk factor for the development of central retinal vein occlusion (CRVO).
Ophthlamiatreion Eye Hospital of Athens, and Department of Ophthalmology, University Hospital of Heraklion, Greece
This was a comparative study of prevalence of pseudoexfoliation in three groups of patients: 48 patients with CRVO, 164 patients with branch retinal vein occlusion and 70 control patients (70 eyes). All patients were phakic and had no diagnosis of glaucoma in their ophthalmic history. Control group was matched in terms of age and systemic hypertension with CRVO group of patients.
In the CRVO group 14 out of 48 patients were diagnosed as having PXF (29.17%). In the BRVO group 14 out of 164 patients had PXF (8.5%) and in the control group 6 out of 70 patients had PXF (8.6%). Differences of percentage between groups were statistically significant (p<0.001, x2 test). When comparing patient subgroup with ischemic CRVO with subgroup with non-ischemic CRVO, we found that in the ischemic CRVO group 13 out of 27 patients were diagnosed as having PXF (48.15%) and in the non ischemic CRVO group 1 out of 21 patients was diagnosed as having PXF (4.7%; p<0.001, x2 test)
PXF and CRVO, especially ischemic, are strongly associated in our study. Our results indicate that PXF is an independent factor for CRVO, as it is correlated with CRVO independently from glaucoma.