First Author: C.Hernaez-Ortega SPAIN
Co Author(s): A. Navea E. Soto-Pedre J. Morales S. Millan P. Perez C. Desco 0 0 0 0 0 0 0 0 0
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To assess the safety of an automated ‘‘disease/no disease’’ grading system for diabetic retinopathy within a systematic screening program.
Cross-sectional observational epidemiologic study.Fundación Oftalmológica del Mediterráneo (FOM), Valencia, Spain.European Innovative Biomedicine Institute (EIBI), Cantabria, Spain.
A single central field digital image per eye was obtained from consecutive patients attending a regional primary care based diabetic retinopathy screening program in Valencia (Spain). Photographers were trained nurse assistants. The sensitivity and specificity of the automated system (iGrading- Medalytix Ltd, Manchester UK - operating as more than one microaneurysm detection for disease presence) grader were determined against a manual grading as gold standard.
5517 patients were screened at twenty-seven Health Centers of four Health Departments. The median age was 69 years (IQR 16 years) and 56% were male. The software classified 44.5% of the patients as having no retinopathy. Detection of retinopathy was achieved with 94.5% sensitivity (95% CI 92.6- 96.5) and 69.1% specificity (95% CI 67.6- 70.6).
Automated grading of diabetic retinopathy based on a single field plus one microaneurysm detection for disease presence approach seems to be adequate not only in terms of workload reduction but also in terms of safety.