First Author: I.Erbagci TURKEY
Co Author(s): E. Ozcan E. Coskun B. Oren S. Okumus 0 0 0 0 0 0 0 0 0
Back to previous
Assessing the changes of intraocular pressure in early period after intravitreal administration of 0.7 mg dexamethasone.
Gaziantep University Faculty of Medicine Department of Ophthalmology
The eyes that we had injected 0.7 mg dexamethasone implant (Ozurdex) between April 2013 and December 2013 were included to the study. The eyes which have ocular hypertension, glaucoma, narrow angle or neovascularization in angle were excluded from the study. Control examinations were carried out at before injection and 1 day, 1 week, 1 month, 2 month and 3 month after injection. In all examination, intraocular pressure (IOP) was measured by applantation tonometer. Also biomicroscopic examination, gonioscopy and fundus examination were carried out. Fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) were performed at before injection and 1 month and 3 month after the injection. We included eyes which we had followed up at least three months to this study. In these monitors, topical IOP lowering treatments were started to the eyes which have intraocular pressure higher than 22 mmHg.
Total 19 eyes of 15 patients that consist of 5 women and 10 men were included to this study. The mean ages of the patients were 58.7±1.2 years. 7 eyes have diabetic macular edema, 9 eyes had macular edema secondary to branch retinal vein occlusion and 4 eyes had macular edema secondary to central retinal vein occlusion. The mean IOP values at before injection and 1 week, 1 month, 2 month, 3 month after the injection were 15.4±2.9 and 15.7±2.7, 15.7±3.3, 18.3±4,6, 15,5±4,5 mmHg respectively. Topical IOP lowering treatment was started for 3 eyes at the 2 month after injection and for 2 eyes at 3 month after injection. Glaucoma surgery was not performed for any eye.
Increment of intraocular pressure which can be controlled with medical treatment can be monitored in early period after intravitreal Ozurdex injection. There is a need for further studies which search long-term results.