First Author: F.J.Ascaso SPAIN
Co Author(s): K. Zabadani L. Herrera C. Caramello C. Almenara N. Cruz J.A. Cristóbal 0 0 0 0 0 0 0 0 0
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We investigate changes in subfoveal choroidal thickness in eyes with diabetic macular edema according to levels of hemoglobin A1c and duration of disease using enhanced depth imaging optical coherence tomography (EDI-OCT).
Department of Ophthalmology, “Lozano Blesa” University Clinic Hospital, Zaragoza, Spain.
57 eyes corresponding to 47 type-2 diabetes patients (mean age 68.3 ± 9.8 49-90 years) who presented with diabetic macular edema were prospectively imaged using EDI-OCT on Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany) SD-OCT. The mean subfoveal choroidal thickness was 221.8 ± 91.9 µm (range, 104-584). The mean level of hemoglobin A1c was 7.5 ± 1.9 mg/dl (range, 5.2-13.4), the measurement of hemoglobin A1c was made over the past two to three months of the study. The mean time of duration of diabetes was 15.5 ± 8.3 years (range, 4-38).
Choroidal thickness measurements at subfoveal area were weakly correlated with serum levels of hemoglobin A1c (r = 0.117, p=0.388). We found a statistically significant negative correlation between duration of disease and subfoveal choroidal thickness (r = -0.304 p= 0.021).
Subfoveal choroidal thickness does not seem to be related to serum levels of hemoglobin A1c. The subfoveal choroidal thickness is negatively correlated with the time course of diabetes mellitus.