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Posters

Choroidal changes in relation to levels of hemoglobin A1c and duration of disease in diabetic macular edema

Poster Details

First Author: F.J.Ascaso SPAIN

Co Author(s):    K. Zabadani   L. Herrera   C. Caramello   C. Almenara   N. Cruz   J.A. Cristóbal   0   0 0   0 0   0 0   0 0

Abstract Details



Purpose:

We investigate changes in subfoveal choroidal thickness in eyes with diabetic macular edema according to levels of hemoglobin A1c and duration of disease using enhanced depth imaging optical coherence tomography (EDI-OCT).

Setting:

Department of Ophthalmology, “Lozano Blesa” University Clinic Hospital, Zaragoza, Spain.

Methods:

57 eyes corresponding to 47 type-2 diabetes patients (mean age 68.3 ± 9.8 49-90 years) who presented with diabetic macular edema were prospectively imaged using EDI-OCT on Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany) SD-OCT. The mean subfoveal choroidal thickness was 221.8 ± 91.9 µm (range, 104-584). The mean level of hemoglobin A1c was 7.5 ± 1.9 mg/dl (range, 5.2-13.4), the measurement of hemoglobin A1c was made over the past two to three months of the study. The mean time of duration of diabetes was 15.5 ± 8.3 years (range, 4-38).

Results:

Choroidal thickness measurements at subfoveal area were weakly correlated with serum levels of hemoglobin A1c (r = 0.117, p=0.388). We found a statistically significant negative correlation between duration of disease and subfoveal choroidal thickness (r = -0.304 p= 0.021).

Conclusions:

Subfoveal choroidal thickness does not seem to be related to serum levels of hemoglobin A1c. The subfoveal choroidal thickness is negatively correlated with the time course of diabetes mellitus.

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