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Sulfur mustard exposure and non ischemic central retinal vein occlusion

Poster Details

First Author: M.Abrishami IRAN

Co Author(s):    N. Shoeibi   M. Balali-Mood               0   0 0   0 0   0 0   0 0

Abstract Details


Sulfur mustard is an alkylating and vesicant chemical warfare agent Central retinal vein occlusion (CRVO) is usually occurred in the elderly and is mostly associated with systemic vascular diseases. We describe a case of CRVO who had no other risk factor except for three times exposure to sulfur mustard during the Iran-Iraq conflict.


Eye Research Center, Department of Retina and Vitreous, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran


In an interventional case report we have evaluated a 41-year-old man who referred with a complaint of visual loss in his left eye.


Best corrected visual acuity was 20/20 in the right eye and 20/80 in the left eye. Slit lamp examination showed arborizing conjunctival vessels and dry eye. Fundus examination and fluorescein angiography revealed a non-ischemic central retinal vein occlusion. Cardiovascular, rheumatologic and hematologic work up showed no abnormal findings. An ascertained history of exposure to sulfur mustard during Iran-Iraq war was documented in his medical history. Four sessions of intravitreal bevacizumab injections were done as needed. After two-year follow-up, visual acuity in his left eye improved to 20/25 and macular edema was resolved without any need for further interventions.


We conclude that sulfur mustard gas exposure may be considered as a predisposing factor for central retinal vein occlusion, as we found it in a young Iranian war veteran by excluding all yet known etiologies and predisposing factors.

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