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Neurosensory macular detachment in multiple evanescent white dot syndrome

Poster Details

First Author: F.Rosales Villalobos SPAIN

Co Author(s):    P. Rivera de Zea   A. González Gómez   J.M. Sandoval Codoni            0   0 0   0 0   0 0   0 0

Abstract Details


To analyze the clinical course and the various manifestations in a case of multiple evanescent white dot syndrome.


54-years old women without any significant background in follow up for acute 2 months anterior uveitis with topical treated with topical prednisolone who complains on bilateral decrease in visual acuity.


Examination revealed visual acuity of 20/ 80 in the right eye and 60/ 80 in the left eye, tyndall + + and funduscopy shows multiple small yellow foci in posterior and peripapillary retinal pole and bilateral papilledema. It was detected by optical coherence tomography a nerosensory detachment in the macular area. On fluorescein angiography appear early hyperfluorescence that increased in later periods in multiple retinal inflammatory foci. Treatment was initiated with oral prednisone 1 mg/kg/day and serology for virus and chest x-ray were negatives.


At 2 weeks the detachment of neurosensory retina and the papilledema have been nearly resolved and visual acuity was 20/20 in both eyes, with lower intensity of the yellow lights that stay 10 weeks after initiation.


Multiple evanescent white dot syndrome (MEWDS) is a rare uveitis, usually unilateral, which presents with numerous small yellowish spots affecting the retinal pigment epithelium and the outer layers of the retina from the posterior pole through mid periphery. Less commonly presents papilledema, mild vitritis, anterior uveitis, vascular sheathing and macular granular appearance. Neurosensory macular detachment is an uncommon clinical sign in MEWDS. The personal history is most often associated with the presence of catarrhal episode in the previous days. The duration of the picture varies between 2 and 8 weeks and runs with good visual prognosis. The syndrome of multiple evanescent white dot is a disease that is still much to learn and detachment of neuroepithelium a rare manifestation of this disease.

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