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Retinal involvement in a patient with Burkitt lymphoma

Poster Details

First Author: P.Romera Romero SPAIN

Co Author(s):    S. Ruiz Bilbao   M. Carbonell Puig               0   0 0   0 0   0 0   0 0

Abstract Details


Burkitt lymphoma is non-Hodgkin lymphoma that originates from B lymphocytes and tends to invade areas outside the lymphatic system and organs of the abdomen, producing rapid growth. The ophthalmologic complications use to be related to immunosuppression satatus, including infectious and immune uveitis.


Analyze the late ophthalmological complications of aplasic patient with Burkitt limphoma.


We present a case of a 54 year old woman having a pelvic mass that was diagnosed as Burkitt's lymphoma, treated surgically and medically with chemotherapy regimen of cyclophosphamide, prednisone and rasburicase. She presented complications as CMV pneumonitis and toxic persistent marrow aplasia. At 12 months of diagnosis she came with decreased visual acuity presenting peripheral inactive retinal scars, compatible with CMV, intrarretinal macular hemorrhages, vitreomacular traction in both eyes with persistent cystoid macular edema and intermitent vitritis.


She required treatment with subtenonian triamcinolone and several doses of intravitreal bevazizumab in both eyes, pars plana vitrectomy and peeling of epiretinal macular membrane in the left eye, showing great anatomical year improvement in both eyes. His final visual acuity was 20/63 in the right eye and 20/500 in the left eye, with significant cataract in the left eye.


We suspect this is a case of immune recovery uveitis, because in the moments of worse visual acuity and greatest vitritis coincided with increased leukocyte counts.

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