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Optic disc granuloma in the course of systemic diseases – diagnostic problems

Poster Details

First Author: E.L.Czaplicka POLAND

Co Author(s):    M. Karolczak-Kulesza   A. Brazert   J. Kociecki            0   0 0   0 0   0 0   0 0

Abstract Details


Optic nerve head granuloma in the course of systemic disease is relatively rare and very often it causes diagnostic and therapeutic problems. Purpose: to present cases of optic disc granuloma in the course of tuberculosis and sarcoidosis.


Case report.


The first case presents optic disc granuloma in a 31-year-old female patient with recurrent uveitis and macular oedema. Etiology of ocular changes was not clear. Mantoux skin test with RT23 antigen and QuantiFERON TB GOLD test were positive. Bronchoalveolar lavage assessment showed no atypical cells. Patient was treated empirically with antituberculosis drugs. Therapy have caused changes regression and visual acuity improvement. Second case presents unilateral deterioration of vision in a 32-year-old female patient with chronic form of lung sarcoidosis. Ophthalmic examination showed right optic nerve head granuloma. Other inflammatory diseases were excluded in differential diagnosis. Changes have resolved after systemic glucocorticosteroid therapy.


Case 1:Tuberculous etiology of change in optic nerve head was confirmed after recurrence of optic disc granuloma and it resolution after again prescribed antituberculosis therapy. Case 2: After several recurrences of right optic disc granuloma, patient developed symptoms of uveitis with typical for sarcoidosis changes in retina.


The authors discuses diagnostic and therapeutic problems of optic disc granuloma in the course of systemic diseases.

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