First Author: H.Kim SOUTH KOREA
Co Author(s): H. Kang D.M. Lee C.S. Lee J.H. Lee S.C. Lee 0 0 0 0 0 0 0 0 0
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To report the results of treatments and therapeutic complications of retinal capillary hemangioblastomas (RCH).
Retrospective, consecutive case series.
Data of 32 patients (37 eyes) with RCH were reviewed for characteristics of RCH, methods of treatment, and visual outcome after treatments.
Twenty four eyes (65%) of 37 eyes had 20/50 visual acuity or better, 8 eyes (22%) had intermediate vision (20/400−20/50), and 5 eyes (13%) had poor vision (≤20/400). Retinal features at diagnosis of RCH included exudation (60%), macular edema (32%), retinal striae (16%), and tractional retinal detachments (8%). After treatment, 89% of small RCHs (<0.5 mm in size) had regressed, whereas only 69% of large RCHs (>3.0 mm in size) regressed (P = 0.044). Peripheral RCHs showed better response to treatment than juxtapapillary RCHs (P = 0.010). Treatment-related complications occurred in 5 eyes (14%) and one-step combination therapy was applied more frequently in the complication group (P=0.048). Transpupillary thermotherapy (TTT) was used in 40 of 73 RCHs and the regression rate of moderate-sized RCHs was 72.2%.
Because RCHs grow continuously, small tumors may require early treatment before they grow larger. In larger RCHs, staged treatment could reduce treatment-related complications. As well, TTT may be of use in treating moderate to large-sized RCHs.