First Author: B.Eldem TURKEY
Co Author(s): S. Kadayifcilar 0 0 0 0 0 0 0 0 0
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To report five cases of choroidal osteoma (CO) complicated with subfoveal choroidal neovascularization (CNV).
Hacettepe University Medical School Department of Ophthalmology
The data of five patients with CO complicated with CNV are reviewed. The best corrected visual acuity (BCVA), fundus findings, fluorescein angiography images, optical coherence tomography findings, and the type of treatment were retrospectively assessed.
There were two males and three females. The age range was 21-59. One male case had bilateral CO with inactive CNV (scar) unilaterally. The other male patient with a VA of 0.2 refused any treatment, and the CNV regressed spontaneously at 3 months with a final VA of 0.3. In the other 3 cases photodynamic therapy (PDT) (The only approved therapy for choroidal neovascularization in year 2005 in Turkey) was performed according to the standart protocol and the cases were followed up every 3 months for at least 5 years. PDT was repeated twice in Case 1: The VA increased from 63 letters to 80 letters at 2 years however decreased to 40 letters at 7 years. In Case 2, the VA did not change at all (From 38 letters to 35 letters). In Case 3, the VA increased from 50 letters to 68 letters at the end of 5 years.
In cases with choroidal osteoma, secondary CNV responded to PDT at the beginning, however in long term, fibrosis resulted in decreased VA in 2 cases. The long term results of further studies assessing antiVEGF therapy for this indication are yet to be seen.