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Choroidal and retinal findings in a patient with immunotactoid glomerulonephritis

Poster Details

First Author: A. Gupta UK

Co Author(s):    R.V. Prabhu   A.K. Patel   R. Sivaraj            0   0 0   0 0   0 0   0 0

Abstract Details


To present choroidal and retinal findings in a patient with cloudy corneas secondary to Immunotactoid Glomerulonephritis (ITG).


Outpatient services at Heart of England Foundation Trust, Sutton Coldfield, UK


57-year-old female was known to have bilateral cloudy corneas diagnosed 12 years ago secondary to Immunotactoid Glomerulonephritis. Clinically, fundus examination was difficult to visualise due to the density of her corneal opacities.


Optical Coherence Tomography (OCT) showed thinning of the inner retinal layers and significant choroidal folds in both eyes. Electrodiagnostic tests (EDT) concluded loss of retinal ganglion cells with preservation of retinal function in both eyes.


The choriocapillaris, Bruch's membrane and RPE complex have been proven to have similar morphological charachteristics as the glomerulus and there is histopathological evidence that immune complexes can get deposited at these sites. Most of this evidence has been described in Type II MPGN. This is the first case describing choroidal folds and retinal involvement in a case with possible ITG. The cloudy cornea in such patients prevents a detailed fundus examination. Serial OCT scans are very useful in monitoring these patients.

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