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Sweep-source optical coherence tomography and wide-field fundus fluorescein angiography imaging of retinal cavernous haemangioma- a new diagnostic imaging gold standard?

Poster Details

First Author: S.Pastor-Idoate UK

Co Author(s):    M. Gil-Martinez   N. Crim   S. Charles   S. Biswas   D. McLeod   P. Stanga   0   0 0   0 0   0 0   0 0

Abstract Details


Cavernous Retinal Haemangioma (CRH) is a rare vascular retinal hamartoma which can present either sporadically or as a dominantly inherited trait. CRH can induce acute visual loss when associated with vitreous haemorrhage, which can be recurrent. Swept-Source Optical Coherence Tomography (SS-OCT) has higher tissue penetration than Fourier-Domain OCT (FD-OCT) due to the utilisation of longer-wavelength (1,050nm). The purpose is to report on a new, non-invasive imaging method for the diagnosis and management of CRH.


Manchester Royal Eye Hospital, Manchester Vision Regeneration (MVR) Lab at NIHR/ Wellcome Trust Manchester CRF, UK


A non-clearing retinal haemorrhage of 6 months duration in a 6 year-old patient was imaged with FD-OCT (3D OCT-2000 FA plus®, Topcon Corp.), SS-OCT (DRI-OCT1 Atlantis®, Topcon Corp, Japan) and Wide-Field Fundus Fluorescein Angiography (WF-FFA) (200Tx®, Optos plc).


FD-OCT showed an intraretinal lesion with cystic-like internal appearance. Significant optical shadowing was present and a diagnosis was not reached. However, SS-OCT showed an intraretinal lesion consisting of a group of grape-like cystic formations with an overlying taut internal limiting membrane (ILM) forming bridges between them. There was no choroidal extension of the lesion. WF-FFA confirmed the diagnosis of CRH. The dimensions of the individual vascular structures and thickness of the vascular walls could be determined using SS-OCT.


This is the first report of the SS-OCT findings in CRH. SS-OCT was superior to FD-OCT in showing the internal anatomy of the CRH, the intraretinal and sub-ILM location of the lesion. SS-OCT allows for a more precise anatomical characterisation of CHR and may help monitor more accurately the lesion and direct management. SS-OCT may become the new non-invasive gold standard imaging method for the diagnosis and management of CRH.

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