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Intraoperative OCT findings in two cases of bilateral macular coloboma in children

Poster Details

First Author: J.M.Marin SPAIN

Co Author(s):    I. Yago                  0   0 0   0 0   0 0   0 0

Abstract Details


To describe the intraoperative OCT findings in two cases of bilateral macular coloboma (MC) in early childhood.


MC is thought to result from incomplete differentiation of the arcuate bundles along the horizontal raphe during development. Consideration of the differential diagnosis is essential because many diseases can mimic this pathology. OCT may be a beneficial tool to make the right diagnosis.


Case 1: A 3-month-old woman was referred to our clinic for the evaluation of strabismus. Ophthalmoscopy showed a bilateral non-excavated scalloped atrophic lesion, with about 2 disc diameters in size, affecting the macula with pigment clumps at the base and edges of the lesion. Case 2: A preterm 6-month-old boy was referred for eye examination to rule out a possible Aicardi Syndrome. The funduscopic examination revealed a macular chorioretinal atrophic scar with associated hyperpigmentation. No other retinal or vascular disorders were detected.


In both cases the immunologic, serologic and electrophysiological testing were normal. The intraoperative portable SD-OCT (iVue, Optovue) revealed a crater-like depression in the macula, demonstrating atrophic neurosensory retina, and an absence of retinal pigment epithelium and choroid in the lesion. Increased backscattering due to bare sclera and choroidal vessels were found.


OCT is helpful for definitely differentiating macular coloboma from other causes of macular pathology such as macular dystrophies and macular degeneration secondary to inflammation.

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