First Author: E.N.Cetin TURKEY
Co Author(s): S. Ergin S. Acer G. Pekel A. Bahar L. Tasli R. Yagci 0 0 0 0 0 0 0 0 0
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To assess whether phototherapy and photochemotherapy for dermatologic diseases affects central macular thickness (CMT) and peripapillary retinal nerve fiber layer (RNFL)
Pamukkale University, Department of Ophthalmology, Department of Dermatology, Denizli, Turkey
The patients who had phototherapy and photochemotherapy for dermatologic diseases were included in this prospective study. The patients with any co-existent diseases that may affect RNFL and macula or prevent optimum imaging were excluded. CMT and peripapillary RNFL were measured by optical coherence tomography (Heidelberg Engineering GmbH, Heidelberg, Germany). The RNFL analysis was performed on 6 sectors including the nasal, temporal, superonasal, superotemporal, inferonasal and inferotemporal sectors and the mean RNFL. The measurements were performed before treatment and 6 months after the beginning of treatment.
A total of 13 patients were included in the study. The mean age was 34.1±17.1. CMT, RNFL thickness in superotemporal, superonasal, temporal, nasal, inferotemporal and inferonasal sectors and the mean RNFL were 221.2±12.6um, 147.6±14.3um, 117.8±22.6um, 69.3±13.5um, 74.6±11.6um, 143.8±14.4um, 106.6±33.8um and 102.0±5.6um respectively before treatment and 223.6±11.4um, 145.3±14.1um, 116.6±22.1um, 70.8±10.0um, 74.9±11.6um, 144.7±12.8um, 115.4±16.6um and 101.5±5.7um respectively 6 months after treatment (p=0.011, p=0.02, p=0.345, p=0.592, p=0.812, p=0.583, p=0.323 and P=0.298 respectively). The change in CMT and RNFL in superotemporal sector was significant.
There was a significant change in CMT and RNFL in superotemporal sector at the sixth month after the beginning of phototherapy and photochemotherapy