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Posters

Endotholial cell abnormalities in patients with several stages of diabetic retinopathy- case-control study

Poster Details

First Author: I.Ammous TUNISIA

Co Author(s):    I. Letaif   Z. Walid   E. Kalil   S. Hela   M. Manel   M. Boussen Ilhem/ last author - Zhioua Raja   0   0 0   0 0   0 0   0 0

Abstract Details



Purpose:

To quantify the morphological alterations in corneal cells in patients with Type 2 diabetes mellitus in relation to the severity of diabetic retinopathy.

Setting:

Charles Nicolle hospital ophthalmology department , Tunis , Tunisia

Methods:

Thirty eyes of 30 patients with Type 2 diabetes and 30 eyes of 30 healthy control subjects were evaluated with in vivo corneal confocal microscopy. Patients with diabetes were classified into three groups: patients without diabetic retinopathy (10 patients), patients with non-proliferative diabetic retinopathy (ten patients) and patients with proliferative diabetic retinopathy (10 patients). Endothelial cell density and cell abnormalities were evaluated.

Results:

Significant reductions in endothelial cell densities were observed in patients with diabetic retinopathy. However, no difference was observed in cellular density between diabetic groups

Conclusions:

Corneal cell pathology occurs in patients with diabetic retinopathy, however diabetic retinopathy stage seems not influencing endothelial cell density and morphology

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