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Sterile endophthalmitis after intravitreal ranibizumab injection

Poster Details

First Author: H.Sımsek TURKEY

Co Author(s):    G. Kaya   Y. Yılmaz               0   0 0   0 0   0 0   0 0

Abstract Details


The injection of intravitreal (IV) Ranibuzumab that caused non-infectious endophthalmitis and its distinctive diagnosis from infectious type are presented.


Dunya Eye Hospital ,Department of Ophthalmologyi,Istanbul, Turkey


The treatment of cystoid macular edema secondary to CNVM ,IVA of 1.25mg/0.05 ml was done and postoperative proflactic topical antibiotic drops were given. Two days later patient came to our hospital with pain and decrease in VA from preinjection level of 0.2 to hand motion. Due to pre-diagnosis of endophthalmitis , vitreous aspiration sample was taken for culture antibiogram and the patient was given the intravitreal, sunconjunctival and systemic antibotic treatment.


VA improved the to 0.05 in postoperative 1st day. The vitreous culture was negative. But due to the reincerease in vitreous opasification and presence of cataract, posterior vitrectomy was performed 1 week after the first operation.Vitritis disappeared and VA improved to 0.1. Two months after first vitrectomy, IV triamsinolon injection was given for macular edema.


Since the development of infectious or noninfectious endophthalmitis after IVA is possible, patients must be monitored closely and given the proper treatment.

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