First Author: A.Sato JAPAN
Co Author(s): E. Fukui N. Senda A. Koshino K. Ohta 0 0 0 0 0 0 0 0 0
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Cuticular drusen are known as small, yellow deposits seen under the retinal pigment epithelium (RPE) and have been reported in eyes with vitelliform macular detachment. The purpose of this study is to report the presence of choroidal neovascularization (CNV) in an eye with cuticular drusen detected by spectral-domain optical coherence tomography (SD-OCT).
Matsumoto Dental University Hospital, Shiojiri, Japan.
Case report of a 65-year-old Japanese woman with cuticular drusen.
A 65-year-old Japanese woman complained of blurred vision in both eyes. At her first ophthalmic examination, her visual acuity was 20/20 in both eyes. Ophthalmoscopy showed many small sub-RPE deposits in both eyes. The SD-OCT images showed nodular elevations of the RPE which had a ‘saw-tooth pattern’. This blunted triangular shape has been reported to be typical for cuticular dusen. Six months after the initial examination, fundus examination showed intraretinal hemorrhage in the left eye, and her visual acuity decreased to 20/40. Fluorescein and indocyanine green angiography (FA/IA) showed early filling of CNV and late leakage. The FA images had a ‘stars-in-the-sky’ appearance in the area of the cuticular drusen, and the SD-OCT images showed subretinal exudative changes with a ‘saw-tooth pattern’. The patient was diagnosed with cuticular drusen associated with CNV.
We detected a CNV in a case with cuticular drusen. We recommend periodic examinations by SD-OCT on eyes with cuticular drusen because cuticular drusen may be a risk factor for CNV.