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Management of endophthalmitis following intra-vitreal treatments

Poster Details

First Author: A.Rehman UK

Co Author(s):    A. Kaintatzis   K. Fotis   H. Eleftheriadisis   M.A. Majid         0   0 0   0 0   0 0   0 0

Abstract Details


The aim of this retrospective chart review was to ascertain the presentation, microbiology, management and outcome of post injection endophthalmitis. Of note, was a cluster of 10 cases.


The review was undertaken in a busy tertiary referral centre


Cases of post injection endophthalmitis were identified from electronic patient records.


Eighteen cases out of 21691 injections were identified giving an overall incidence of 0.08%. 61% of patients presented with pain. The average time from the intra-vitreal injection to presentation at the eye casualty was 5 days. The most common cause was staphylococcus species with a few sterile cases. 50 % of patients underwent early pars plana vitrectomy and 44% received systemic steroids. The mean vision at presentation was 2.3 LogMar and the mean post treatment vision was 0.7 LogMar. In the cluster group, no unusual features or bacterial strains were identified. However, a strict review of procedures led to a subsequent reduction in incident cases.


Prompt intra-vitreal antibiotics and vitreous / anterior chamber sampling remains the cornerstone of initial management. No clear association between the bacteriology and the visual outcome was noted. Early vitrectomy should be considered to allow rapid rehabilitation.

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