First Author: D.Costin ROMANIA
Co Author(s): A. Moraru D. Branisteanu 0 0 0 0 0 0 0 0 0
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Assessment of the risk of neovascular age related macular degeneration (AMD) progression in patients receiving anti-VEGF intravitreal treatment on a treat and extend basis who underwent cataract surgery.
N. Oblu Hospital, Iasi, Romania; Gr. T. Popa University of Medicine and Pharmacy Iasi, Romania
The retrospective study included 21 patients diagnosed with advanced neovascular AMD who underwent cataract extraction by phacoemulsification. 9 patients had subfoveal choroidal neovascular membranes and in 12 patients the lesions were extrafoveal. All the patients had at least three intravitreal injections of Bevacizumab (on a treat and extend basis) before cataract surgery and the macular lesions did not show any sign of progression in the last two months. Visual acuity was measured before and after surgery and 3D OCT images were acquired at each visit. All patients were monitored once a month at least six months.
The mean visual acuity in the study group before cataract surgery was 0,12+/-0,34 and the mean central macular thickness measured by OCT was 278+/-62 μm. No complications related to cataract extraction were recorded. The mean visual acuity at one month after surgery increased at 0,3+/-0,16 and remained stable during the follow up period. The mean central macular thickness recorded at one month was 294+/-37 μm and showed no major changes at 6 months. The anti-VEGF treatment was continued on a treat and extend basis during the follow up.
The risk of neovascular AMD progression did not increase after uncomplicated phacoemulsification surgery. Cataract surgery showed benefits in visual acuity improvement and better OCT surveillance of macular lesions.