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Double masked evaluation of the management of neovascular age related macular degeneration by spectral domain OCT images

Session Details

Session Title: Quick Fire Free Paper 5

Session Date/Time: Sunday 14/09/2014 | 11:00-13:00

Paper Time: 12:10

Venue: Boulevard B

First Author: : B.Kapoor UK

Co Author(s): :    V. Konidaris   F. Mustaq   T. Empeslidis        

Abstract Details


To evaluate the agreement on treatment decisions of two retinal specialists in the management of neovascular AMD with antivascular endothelial growth factors (anti-VEGF) based on assessment of OCT.


Department of Ophthalmology, Leicester Royal Infirmary, Leicester UK


Two masked retinal specialists reviewed 196 OCT images (TOPCON 3D OCT-1000) of 196 patients treated for neovascular AMD (121 female, mean age 80.5 ± 7.78 years). Treatment decisions were based on the presence of subretinal fluid (SRF), intraretinal fluid (IRF), central retinal thickness (CRT) as well as the patients’ best corrected visual acuity.


The mean CRT was 241.45 ± 61.24 μm. There was 100 % agreement among the two retinal specialists on presence of SRF. In 3/196 (1.53%) of the cases there was a disagreement concerning the presence of IRF. Decisions concerning anti-VEGF treatment were different in 12/196 (6.12%) of the cases.


There was good agreement among the two retinal specialists. The variation on assessment of IRF could be due to the presence of intraretinal cysts, whose activity was appraised differently by the two specialists. The discrepancy in the management plan was attributable to the different estimation of the activity of the lesions found on the OCT.

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