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The analysis of risk factors for the radiation retinopathy following ruthenium brachytherapy of uveal melanoma

Session Details

Session Title: Quick Fire Free Paper 4

Session Date/Time: Sunday 14/09/2014 | 08:00-10:00

Paper Time: 09:30

Venue: Boulevard B

First Author: : I.Rospond-Kubiak POLAND

Co Author(s): :    J. Kociecki              

Abstract Details


to evaluate the risk factors for radiation retinopathy following the ruthenium brachytherapy of uveal melanoma


retrospective case analysis


The records of the patients treated due to uveal melanoma at the Department of Ophthalmology, Poznan University of Medical Sciences between 1991-2005 were analysed. The outcomes in terms of radiation retinopathy were correlated to the initial tumour characteristics using a StatSoft, Inc. (2011) STATISTICA, version 10.


64 patients (26 men, 38 women) had a mean age of 57,22 years. Mean largest basal diameter of the treated melanomas was 11,62 mm and mean thickness - 5,18 mm. Standard apical dose was 100 Gy. 38 patients had additional transpupillary thermotherapy, 8 (12,5 %) globes were enucleated, of wihich 4 due to neovascular glaucoma, 4 due to marginal recurrence. 25 patients died (39 %), 13 of metastatic disease (20 %). 25 patients (39 %) had the symptoms of radiation retinopathy. The risk factors for the radiation retinopathy were: largest basal diameter at presentation (p=0,00046) and tumour location close to the macula (p=0,0001). In most of the patients the symptoms of the radiation retinopathy appeared 4 years after the treatment.


Radiation retinopathy was more likely to appear for the tumours with bigger largest basal diameter at presentation and situated close to the macula.

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