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Evaluation of Choroidal Thickness during Pregnancy using Enhanced Depth Imaging Optical Coherence Tomography

Session Details

Session Title: Quick Fire Free Paper 2

Session Date/Time: Thursday 11/09/2014 | 11:00-12:30

Paper Time: 11:30

Venue: Boulevard D

First Author: : R.Rothwell PORTUGAL

Co Author(s): :    D. Meira   M. Oliveira   L. Ribeiro   S. Fonseca     

Abstract Details

Purpose:

To evaluate choroidal thickness and volume during the third trimester of pregnancy.

Setting:

Department of Ophthalmology, Gaia Hospital, Portugal

Methods:

Twelve pregnant women in the last trimester and 12 age-matched healthy controls (48 eyes) were included. Optical coherence tomography in enhanced depth imaging mode was used to construct maps of the choroid of the macular area. Choroidal thickness and volume were automatically calculated for the 9 subfields defined by the Early Treatment Diabetic Retinopathy Study (ETDRS).

Results:

The average thickness of the choroid for the entire ETDRS area of the pregnant women was 295.15 ±42.40μm and 271.56 ±37.65μm in the control group (p=0.051). The average choroidal volume was 8.05 ±1.12mm3 and 7.46 ±1.03mm3, respectively (p=0.067). Although the choroid of the pregnant group of women had larger thickness and volume in all subfields, this difference was statistically significant only in the central subfield, minimum foveal thickness and inferior inner macula (p<0.05).

Conclusions:

Our study suggests that in the third trimester of pregnancy the choroid may be subject to physiological changes in structure. These changes may be related to the physiological increase in serum cortisol and help to explain the increased risk of central serous chorioretinopathy during pregnancy.

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