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Evaluation of choidal thickness in relation with gender, age, axial length and refractive error in young Turkish population

Session Details

Session Title: Quick Fire Free Paper 2

Session Date/Time: Thursday 11/09/2014 | 11:00-12:30

Paper Time: 11:15

Venue: Boulevard D

First Author: : G.Satirtav TURKEY

Co Author(s): :    G. Kaya   M. Donbaloglu   H. Kerimoglu   R. Oltulu     

Abstract Details

Purpose:

To determine the average choroidal thickness and to evaluate the changes according to age, gender, refractive error and axial length in otherwise healthy young Turkish individuals.

Setting:

Necmettin Erbakan University School of Medicine, Konya, Turkey

Methods:

Six hundred and eighty four eyes of 342 healthy young volunteers were enrolled in the prospective cross-sectional study. Enhanced depth imaging (EDI) taken by spectral domain optical coherence tomography (OCT) was obtained and subfoveal choroidal thickness (SCT) was measured manually for each subject. Interferometric axial length (AL), objective refraction and best corrected visual acuity (BCVA) measures were obtained and the associations between datas were analysed statistically.

Results:

There were 174 females and 168 males, with an average age of 23,8± 6,6 years (range: 10-40). The overall mean SCT was 327.5 ±76.8 µm (122 − 535 µm). Mean SCT in females was 331.6 ±76.1 µm and in males was 323.2 ±77.5 µm and the difference between the genders was not statistically significant. Multiple regression analysis was performed for age, AL and RE. There was a positive correlation between SCT and age with 2,2 µm change in SCT for every year of age when adjusted for sex and axial length. (95% confidence interval: 1.3−3.1 µm, R² = 0.35, P<0.000). Mean AL was 24.07 ±1.22 mm (19.9 − 27.5 mm) and a negative correlation with SCT was determined with 29,6 µm of increase in SCT for every 1mm of AL when adjusted for age and sex. (95% confidence interval: -33.8−-25.5 µm, R² = 0.223, P<0.000). A positive correlation between refractive error (RE) and SCT was found with 16,9 µm change for every diopter change in RE when adjusted for age and sex. (95% confidence interval: 14.7−19.0 µm, R² = 0.258, P<0.000).

Conclusions:

In this study of healthy young individuals, SCT reveals significant association with age, axial length and refractive error. This observation may help in highlighting pathogenesis of different ocular diseases revealing change in these parameters.

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