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Retinal layers measurements in healthy eyes and in eyes receiving silicone oil-based endotamponade

Session Details

Session Title: Quick Fire Free Paper 2

Session Date/Time: Thursday 11/09/2014 | 11:00-12:30

Paper Time: 11:00

Venue: Boulevard D

First Author: : A.Caramoy GERMANY

Co Author(s): :    K. Droege   B. Kirchhof   S. Fauser        

Abstract Details

Purpose:

To characterize the concordance/symmetry of each retinal layers in individuals without macular pathology and to further characterize the localization of inner retinal thinning in eyes receiving silicone oil-based endotamponade.

Setting:

University Eye Hospital of Cologne, Germany

Methods:

One hundred eyes of 50 individuals without macular pathology were manually segmented using ImageJ software (developed by Wayne Rasband, NIH, Bethesda, Maryland, USA). In the second part of the study, retrospective analysis of 3,028 cases of pars plana vitrectomy in University Eye Hospital Cologne, Germany was conducted, retrieving 9 patients with silicone oil-based endotamponade with no macular condition interfering retinal layers measurements. In these patients retinal layer segmentation was performed and compared to the fellow eye.

Results:

There is a moderate to high concordance for all retinal layers between the right and the left eye of the same individual. In eyes receiving silicone oil-based endotamponade the inner retinal layers become subsequently thinner. Ganglion cell and inner plexiform layers contribute most to this thinning. Outer retinal layers were not affected by silicone oil-based endotamponade.

Conclusions:

Ganglion cell and inner retinal layers become subsequently thinner after the use of silicone oil-based endotamponade. This study advocates the use of spectral-domain optical coherence tomography for patient management with silicone oil endotamponade to early detect subsequent retinal thinning.

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