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Evaluation of topical alpha-2 agonist in the treatment of mixed diabetic maculopathy

Session Details

Session Title: Quick Fire Free Paper 1

Session Date/Time: Thursday 11/09/2014 | 08:00-10:00

Paper Time: 08:25

Venue: Boulevard D

First Author: : H.Al-Nashar EGYPT

Co Author(s): :                  

Abstract Details

Purpose:

To evaluate the efficacy of topical alpha-2 agonist (brimonidine) in the treatment of diabetic maculopathy with mixed edema and ischemia

Setting:

Patients are in the Zagazig University Hospitals, Zagazig, Sharkya, Egypt.

Methods:

Twenty two eyes of twenty two patients are involved in this study. All eyes have mixed diabetic maculopathy as diagnosed by fluorescein angiography and spectral domain optical coherence tomography (SD-OCT) (Spectralis HRA-OCT; Heidelberg engineering, Heidelberg, Germany). They were treated by topical brimonidine twice daily for 3 months. Visual acuity, fluorescein angiography & OCT were done for all patients before the beginning of the treatment and every one month for 3 months later on to detect the change in ligMAR visual acuity and the changes in foveal avascular zone (FAZ) size and the macular thickness.

Results:

The mean logMAR visual acuity at the beginning of the treatment was 0.9±0.012 and improved to 0.7±0.1 after 3 months (P= 0.03). Size of FAZ was improved after the treatment. The mean central macular thickness was 425±125 µm and changed to 400±23 µm after 3 months (P=0.9).

Conclusions:

Alpha 2 agonist (brimonidine) has a role in the treatment of mixed diabetic maculopathy

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