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Correlation of preoperative retinal pigment epithelium status with foveal microstructure in repaired macular holes

Session Details

Session Title: FP-16 Vitreoretinal Surgery IV

Session Date/Time: Sunday 14/09/2014 | 11:00-13:00

Paper Time: 11:32

Venue: Boulevard D

First Author: : C.Mariotti ITALY

Co Author(s): :    M. Reibaldi   M. Nicolai   A. Saitta        

Abstract Details


To investigate, with spectral-domain optical coherence tomography, if the preoperative status of the retinal pigment epithelium (RPE) can affect the post-operative foveal morphology and visual outcomes in eyes with surgically closed macular holes (MHs).


Department of Ophthalmology of the University of Ancona, Italy.


In 52 eyes with surgically closed MHs, preoperative RPE morphology, 12 months after surgery foveal microstructural features, and best-corrected visual acuity (BCVA) were evaluated


At 12 months, a significantly correlation was found between postoperative degree of integrity of the photoreceptors with preoperative RPE line status, and base diameter of the hole (respectively P=0.003 and P=0.028, regression analysis); mean BCVA at 12 months in the group of eyes with diffuse RPE line alteration was significantly lower than in eyes of other two groups (small or no RPE alteration) (Tukey–Kramer test P<0.05).


Preoperative RPE layer integrity may be indicative of good photoreceptor restoration and visual recovery in patients with surgically closed MHs

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