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Wide-field fundus autofluorescence and swept-source-optical coherence tomography imaging findings as predictor of visual outcome after successful retinal detachment surgery

Session Details

Session Title: Imaging III

Session Date/Time: Saturday 13/09/2014 | 14:30-16:00

Paper Time: 15:18

Venue: Boulevard C

First Author: : M.Gil SPAIN

Co Author(s): :    S. Pastor-Idoate   A. Jalil   J. Garcia-Vallejo   T. Ivannova   S. Charles   P. Stanga

Abstract Details


To analyse retinal pigment epithelium (RPE) and neuroretinal (NR) changes on Wide-Field Fundus Autofluorescence (WF-FAF) and Swept-Source Optical Coherence Tomography (SS-OCT) imaging after successful rhegmatogenous retinal detachment (RD) surgery.


Manchester Royal Eye Hospital, Manchester Vision Regeneration (MVR) Lab at NIHR/ Wellcome Trust Manchester CRF, Academic Health Science Centre and Centre for Ophthalmology and Vision Research, Institute of Human Development, University of Manchester, UK


Retrospective, non-interventional study. We analysed the images of 23 patients (24 eyes) who underwent RD surgery. All patients were post-operatively imaged using wide-field colour and fundus autofluorescence (200TX®, Optos plc.) and 1,050nm SS-OCT (Atlantis Deep Range Imaging OCT1®, Topcon Inc.). All images were analysed by three independent observers.


The mean age of the patients of this study was 57.21±13.78 years old. The macula was preoperatively OFF in 14 eyes and ON in 11. Of the patients with RD, 45.8% (n=11) underwent pars plana vitrectomy (PPV), endolaser and intraocular injection of gas, 33.3% (n=8) PPV plus cryotherapy and 20.83% (n=5) received cryobuckle surgery. The post-operative visual acuity (VA) improved in 100% of the patients. However, in two of them the VA was subsequently reduced due to the development of an epiretinal membrane (EM) and macular oedema (MO). The reported post-operative symptoms included: metamorphopsia, central blurred vision and diplopia. We found an abnormal autofluorescence pattern in 85.71% of the macular OFF detachments and in 37.5% of the macula ON ones. Macula OFF detachment was associated with abnormalities in the outer retina on SS-OCT in 84.61% of the patients with macula OFF RD compared to 27.27% with macula ON RD.


WF-FAF and SS-OCT imaging following RD surgery can be useful for evaluating RPE function and structural changes in the neuroretina, thus explaining visual outcome. Further studies are required to determine pre-operative markers of post-operative improvement in vision.

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