Session Title: Imaging III
Session Date/Time: Saturday 13/09/2014 | 14:30-16:00
Paper Time: 15:10
Venue: Boulevard C
First Author: : G.Yilmaz TURKEY
Co Author(s): : N. Yesilirmak S. Gur Gungor E. Yaman Pinarci I. Akkoyun
Purpose: To evaluate the changes in choroidal thickness (CT) at thirteen different points between “active”, “remission” and “end stage” phase of Behcet’s panuveitis (BP) and compare this with the age, sex and spherical equivalent matched healthy controls using the Spectralis enhanced depth imaging optical coherence tomography (EDI-OCT).
Baskent Unıversity, Faculty of Medicine, Department of Ophthalmology
Methods: The retrospective case control study consisted of 43 patients with BP and 42 controls. Thirteen CT measurements were obtained beneath the fovea and at 500 µm intervals for 3 mm nasal and temporal to the centre of the fovea with using EDI-OCT. Main outcome measures consisted of CT, disease duration, age and sex.
Results: Submacular choroidal thickness was significantly thinnest in patients with end-stage phase BP and thickest in patients with active phase BP (p<0.01). Significant differences were found at all temporal CT between “patients with end-stage phase BP” and “patients with active and remission phase BD” (p<0.01). The mean CT at each of the thirteen measured points showed a positive correlation with visual acuity and showed a negative correlation with age and disease duration in BD patients.
Conclusions: Submacular CT, as measured by EDI–OCT, was significantly reduced in patients with end-stage phase BP and increased in patients with active phase BP. Further research is needed to confirm this study, to understand the pathophysiological alterations in BD better and to determine best treatment timing.