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The progression rate of retinal pigment epithelium atrophy in punctate inner choroidopathy

Session Details

Session Title: Imaging III

Session Date/Time: Saturday 13/09/2014 | 14:30-16:00

Paper Time: 14:30

Venue: Boulevard C

First Author: : R.Hua CHINA

Co Author(s): :    L. Chen              

Abstract Details

Purpose:

To investigate the progression rate of retinal pigment epithelium (RPE) atrophy lesions in punctate inner choroidopathy (PIC) based on confocal scanning laser ophthalmoscopy fundus autofluorescence (FAF) imaging.

Setting:

Retrospective study in China

Methods:

22 eyes of 14 PIC cases and 21 eyes of 21 non-proliferative diabetic retinopathy (NPDR) cases received retinal coagulation as control group were enrolled in this prospective study. Macular 30 degree Blue light FAF (BL-FAF, excitation 488 nm, emission 500–700 nm) images were recorded from all patients. At all visits, the RPE atrophy area of PIC lesions and laser scars in NPDR was analyzed using the region finder software of Heidelberg eye explorer. The software allows direct export of FAF images from the database and semiautomated detection of atrophic areas by shadow correction, vessel detection, and selection of seed points.

Results:

The mean progression rate of RPE atrophy in PIC and NPDR were 3.735 mm2/year (0.056-0.545) and 0.127 mm2/year (0.015-0.466). Compared with the atrophy area in the last visit, the progression rate in PIC was significant greater than that in NPDR (Z=5.615, p<0.0001).

Conclusions:

This is the first report on the progression rate of RPE atrophy in PIC, which can be used to predict the state of this disease noninvasively.

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