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Laser photocoagulation in retinopathy of prematurity and prognostic factors

Session Details

Session Title: Vascular Diseases and Diabetic Retinopathy III

Session Date/Time: Friday 12/09/2014 | 16:30-18:00

Paper Time: 17:10

Venue: Boulevard D

First Author: : S.Sizmaz TURKEY

Co Author(s): :    E. Esen   A. Sariyeva   N. Demircan        

Abstract Details

Purpose:

To analyze the efficiency of laser photocoagulation (LP) in retinopathy of prematurity (ROP) and investigate the features that could affect the outcome.

Setting:

Cukurova University, School of Medicine, Department of Ophthalmology, Adana, TURKEY

Methods:

Medical records of patients who underwent LP for ROP between January 2012 and July 2013 were retrospectively reviewed. Prior to LP gestational age, gestational weight, zone and stage of the disease, as well as existence of plus disease, hemorrhage, preexisting fibrovascular proliferation, tunica vasculosa lentis, and vitreous haze were assessed. Postconseptional age at LP, need for additional LP, and development of post-LP fibrovascular traction were also evaluated. Attached retina at the end follow-up was considered the mean outcome measure. Correlations between the variables and outcome were made by student t test and Mann Whitney U test.

Results:

One hundred twenty six eyes of 64 infants were enrolled. Twenty six (20.6%) eyes progressed to retinal detachment (Grade 4B). The mean (± standard deviation) gestational age was 28.22.3 weeks in eyes that had favorable outcome and 26.8±1.9 weeks in eyes with poor prognosis (p=0.06). The mean gestational weight in patients with favorable and poor outcome were 1152.9±384.5 and 879.6±172.1, respectively (p=0.02). Of the pre-LP parameters evaluated, zone and stage of the disease (p=0.04 and 0.001, respectively), hemorrhage (p=0.03), tunica vasculosa lentis (p=0.0001), vitreous haze (0.005) found to significantly correlate with prognosis. Post-LP fibrovascular traction and need for additional LP also found to significantly affect the prognosis (p=0.001 and 0.005 respectively). Tunica vasculosa lentis and vitreous haze found to significantly affect the need for additional LP (p=000.1 for both).

Conclusions:

Gestational age, existence of plus disease, tunica vasculosa lentis, vitreous haze, and post-LP fibrovascular traction were the most prominent factors associated with poor prognosis in ROP cases that underwent LP.

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