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Macular thickness in a French population over 75 years old (Montrachet’s study- maculopathy, optic nerve, nutrition, neurovascular and heart diseases)

Session Details

Session Title: Imaging II

Session Date/Time: Friday 12/09/2014 | 16:30-18:00

Paper Time: 17:10

Venue: Boulevard C

First Author: : O.Fleck FRANCE

Co Author(s): :    P. Koehrer   S. Vinault   C. Tzourio   A.M. Bron   C. Binquet   C. Creuzot Garcher

Abstract Details


The aim of our study was to describe normal macular thickness in a large sample from old French population over 75 years old.


Department of Ophthalmology, University Hospital, Dijon, France


Three city study (3C) included 9294 subjects aged 65 years or more from three cities (Bordeaux, Dijon and Montpellier) in 1999. After a 10 years’ follow up, Dijon’s cohort had a complete ophthalmic examination in the MONTRACHET study. One thousand one hundred fifty three patients over 75 years were included. All patients had refraction test, ETDRS visual acuity, fundus photographs, macular thickness measured by spectral-domain optical coherence tomography in the inner ring determined by the ETDRS. Patients with severe ametropia, early or late forms of age related macular degeneration, retinal hemorrhages or glaucoma were excluded.


Six hundred eighty seven eyes (342 right, 345 left eyes) from 347 patients were selected. Mean age was 81.5 ± 3.6 years, 60.8% (211) were women. The mean macular thickness of right eyes was 279.17 ± 25.48 µm in the central subfield and 323.77 ± 17.62 µm in the whole inner ring. There was no significant difference in macular thickness in central subfield or inner ring between right and left eyes (p=0.514 ; p=0.267). The macular thickness in central subfield was significantly higher in men than in women (p=0.0003). Nasal macular thickness was significantly higher than temporal one in both eyes (p<0.0001). We did not find any correlation between visual acuity and macular thickness in central subfield or in the whole inner ring neither in right eyes (r=0.102, p=0.060; r=0.021, p=0.699) nor in left eyes (r=0.060, p=0.271; r=0.035, p=0.514).


Our results were similar to previous studies in other cohorts. This is the first study which aims at describing macular thickness in elderly population with healthy eyes. It will be useful to establish normative values in this age subgroup.

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