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Swept-source optical coherence tomography assessment of the cortical vitreous and choroidal thickness in different macular disorders

Session Details

Session Title: Imaging II

Session Date/Time: Friday 12/09/2014 | 16:30-18:00

Paper Time: 17:02

Venue: Boulevard C

First Author: : S.Pastor-Idoate UK

Co Author(s): :    M. Gil-Martinez   S. Charles   S. Biswas   D. Henson   D. McLeod   P. Stanga

Abstract Details


To determine the prevalence of the Bursa Premacularis (BPM) and Space of Martegiani (SM) and assess Choroidal Thickness (CT) in healthy eyes (HE) and in eyes with various macular disorders (MD) using Swept-Source Optical Coherence Tomography (SS-OCT).


Manchester Royal Eye Hospital, Manchester Vision Regeneration (MVR) Lab at NIHR/ Wellcome Trust Manchester CRF, UK


Retrospective, comparative and non-interventional study. 113 consecutive patients underwent 1,050nm SS-OCT (DRI-OCT1 Atlantis®, Topcon Corp, Japan). The prevalence of the BPM and SM was assessed in HE and MD. Macular CT was determined by measuring the distance between the retinal pigment epithelium (RPE) and the choroid/sclera junction at three sites along a 500µm line centred on the fovea in 53 HE and 138 MD. Patients were categorised into 8 groups; (Diabetic Retinopathy (19), Age-Related Macular Degeneration (AMD) (32), High Myopia (HM) (22), Vitreomacular Adhesion (VMA) and/or Epiretinal Membrane (ERM) (11), Central Serous Retinopathy (CSR) (9), Retinitis Pigmentosa (RP) (9) and Miscellaneous (10).


Mean age was 47±23 years for HE versus 57±22 years for MD (p<0.05 U Mann Whitney). Mean CT was 251±93μm for HE versus 218±104μm for MD (p=0.041 U Mann Whitney). BPM was present in 66% of HE (35) versus 31.9% of MD (44) (p<0.05 Fisher’s test). SM was present in 54.7% of HE (29) versus 32.6% of MD (43) (p<0.004 Fisher’s test). Sub-group analysis showed significant differences in CT between HE and MD with AMD, HM, VMA and/or ERM, CSR and RP (p<0.05 U Mann Whitney).


SS-OCT allows the assessment of the cortical vitreous and prevalence of the BPM and SM as well as the measurement of CT in different macular pathologies. The BPM and SM were more prevalent in HE. A thin choroid may be associated with the AMD, High Myopia and VMA/ERM groups and a thick one with the CSR group.

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