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Variability of choroidal thickness measurements in choroidal nevi using enhanced depth optical coherence tomography

Session Details

Session Title: Imaging I

Session Date/Time: Friday 12/09/2014 | 11:00-13:00

Paper Time: 11:24

Venue: Boulevard D

First Author: : A.Arora UK

Co Author(s): :    E. Pavlidou   K. Kopsidas   V. Papastefanou   V. Cohen   M. Sagoo  

Abstract Details


To evaluate the variability in choroidal thickness measurements in patients with choroidal nevi imaged on spectral domain optical coherence tomography (OCT), using enhanced depth imaging technique (EDI).


Dept of Ocular Oncology, London


Fifty eyes of 50 patients with a choroidal nevus were enrolled in this retrospective observational study. Horizontal line scans through the choroidal naevus were obtained for each eye. Using the manual callipers provided by the software of the device, two OCT readers measured the choroidal thickness based on EDI-OCT images. The coefficient of reproducibility (CR) within graders was used as a measure of relative reliability and assessed using Bland-Altman plots.


50 eyes with choroidal nevi imaged with EDI OCT displayed image detail were suitable for study. The mean (SD) choroidal thickness from the first grader was 855 μm (378) μm while from the second was 860 μm (372 μm). The mean difference was 54 μm (105 μm) (p>0.005). The interobserver CR was approximately 456 (95% CL, 335-573 μm).


The choroid can be assessed with good reliability but the inherent relative variability in measurements should be considered when investigating eyes with pathologic conditions related to a thick choroid such as choroidal naevus.

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