Session Title: Imaging I
Session Date/Time: Friday 12/09/2014 | 11:00-13:00
Paper Time: 11:16
Venue: Boulevard D
First Author: : J.Ruiz-Medrano SPAIN
Co Author(s): : I. Flores-Moreno P. Peña-García J.A. Montero J.S. Duker J.M. Ruiz-Moreno
To determine choroidal thickness (CT) profile in a healthy population using swept-source optical coherence tomography (SS-OCT).
Retina department, Vissum Alicante, Spain
Cross-sectional, non-interventional study. 276 eyes from 154 healthy patients, with spherical equivalent (SE) between ±3D, were scanned using a SS-OCT (Topcon Corporation, Japan). A horizontal CT profile of the macula was created by manually measuring the subfoveal CT (SFCT) from the posterior edge of retinal pigment epithelium (RPE) to the choroid/sclera junction. Three further determinations were performed at successive points 1000 m nasal to the fovea and five more temporal to the fovea. The subjects were divided into five groups according to age. The mean age was 33.5±24.9 years (from 3 to 95). The mean SE was 0.10±1.36 D.
SS-OCT allowed the measurement of the CT in all eyes (100%). The mean SFCT was 301.89±80.53 m (95% confidence interval: 292.34 to 311.43). The mean horizontal macular CT (MCT) was 258.69±64.59m (95% confidence interval: 251.04 to 266.35). No difference in CT was found between men and women (mean SFCT 303.9±70.9 m vs. 296.4±94.1 m; P= 0.483; Student t test and mean horizontal MCT 260.8±60.9 m vs. 255.0±70.7 m, P= 0.227; Mann Whitney U test, respectively). Mean SFCT of the different study groups was 325.6±51.1 m in 0 to 10 years, 316.7±90.1 m in 11 to 20 years, 313.9±80.3 m in 21 to 40 years, 264.6±79.3 m in 41 to 60 years and 276.3±88.8 m in more than 60 years (P<0.001; ANOVA test). Mean horizontal MCT was 286.0±43.5 m, 277.7±68.2 m, 264.0±61.9 m, 223.4±62.2 m and 229.7±66.1 m for 0 to 10, 11 to 20, 21 to 40, 41 to 60 and > 60 years respectively (P<0.001; ANOVA test). The CT profile was different for each group of age.
To our knowledge, this is the first population study of CT of healthy eyes across a broad range of age groups using SS OCT. As has been determined using spectral domain SD OCT, CT decreases with advancing age, especially after age 40. There were no differences in CT due to gender. The greatest CT variation due to age takes place in temporal sectors.