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Efficacy of micropulse 532 NM green laser in diabetic macular edema

Session Details

Session Title: Vascular Diseases and Diabetic Retinopathy II

Session Date/Time: Friday 12/09/2014 | 11:00-13:00

Paper Time: 11:00

Venue: Boulevard C

First Author: : K.Sousa PORTUGAL

Co Author(s): :    C. Ferreira   L. Mendonça   R. Gentil   R. Leite   F. Vaz   N. Gomes

Abstract Details


To evaluate our results using a 577 nm green micropulse laser for the treatment of diabetic macular edema.


Ophthalmology department of Hospital de Braga, Portugal.


This was a retrospective study of patients that were submitted to micropulse laser for the treatment of center-involving diabetic macular edema. We used a 577 nm green laser (Quantel SupraScan® 532nm) on areas of leakage as determined by fluorescein angiography. A subthreshold retinal photocoagulation was applied with a 10% duty-cycle of 200ms, 70% corresponding power of other retinal areas and a 50μm spot diameter. Best-corrected visual acuity (BVCA) was measured before and two-month after treatment. All the patients underwent SD-OCT, autofluorescence imaging (FAF) and fluorescein angiography (FA) before and after treatment. Retreatment criteria include aggravating edema, low visual acuity and target-lesion placed in no recommending conventional laser.


We analyzed 68 eyes of 50 patients that were treated with micropulse laser in our department. Forty-one of these were female. Mean age was 64.8 (45-84) years old. Central macular thickness variation after treatment ranged from -175μm to +138μm (mean variation: -17,96±47.1μm; p=0.002 vs. baseline; paired-sample-test). Mean BCVA improved 0.01 on decimal scale (p>0,05; paired-sample-test). FAF showed no changes after treatment but there was a decrease in the area of leakage on fluorescein angiography. There were no visible laser scars on any of the exams performed. Five patients had to repeat the treatment due to a lack of response. They all showed improvement after the second treatment.


Micropulse 532 LASER alone was shown to reduce macular thickness and improve BCVA in diabetic patients with center-involving macular edema. One treatment is generally enough to cause an improvement in thickness or a decrease in leakage as seen on SD-OCT or fluorescein angiography. There were no visible scars on fundus exam, FAF and FA. Micropulse 532 LASER could be considered in in the treatment of center-involving diabetic macular edema, either alone or combined.

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