Session Title: Vascular Diseases & Anterior/posterior segment surgery
Session Date/Time: Sunday 29/09/2013 | 11:00-13:00
Paper Time: 12:12
Venue: Hall 3 (Level 0)
First Author: S.Solborg Bjerrum DENMARK
Co Author(s): K. Lyngby Mikkelsen M. la Cour -. - -. -
To study the risk of pseudophakic retinal detachment (PRD) after first eye phacoemulsification cataract surgery in Denmark relative to the risk of retinal detachment (RD) in the patients’ fellow non-operated eyes
Register based cohort study of 202,226 patients
All patients had uncomplicated first eye phacoemulsification cataract surgery from 2000-2010. Surgeries were identified via the National Patient Registry in Denmark and the Civil Registration Number. The fellow non-operated eye was used as a reference.
We identified 110 RDs in the fellow non-operated reference eyes. In these eyes male sex and younger age were significantly associated with greater risk of RD. We identified 465 PRDs on the cataract operated eyes. The relative risk of PRD was 4.23. This effect of cataract surgery on the relative risk of RD (the PRD risk ratio) was only discreetly modified by sex and age. The PRD risk ratio was insignificantly higher in men compared to women (hazard ratio=1.26). The PRD risk ratio was highest for the 40- and lowest for the 80-year olds. The PRD risk ratio was highly increased during the first six months postoperatively and leveled off but remained significantly elevated up to ten years after cataract surgery.
Using the fellow non-operated eye as a reference, this comprehensive matched design cohort study clearly separates the epidemiology of occurrence of RD from the relative risk of PRD. The epidemiology of RD in the fellow eyes was strongly predicted by age and sex. The fourfold increase in risk associated with cataract operation, the PRD risk ratio, was only discreetly modified by sex and age. The long follow-up time demonstrated a persistently significantly elevated relative risk of PRD up to 10 years after cataract surgery. As the fellow eye was used as reference the PRD risk ratio can be considered a true etiological effect of cataract surgery.