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Intracameral bevacizumab for intraocular pressure control in patients with neovascular glaucoma

Session Details

Session Title: Vascular Diseases & Anterior/posterior segment surgery

Session Date/Time: Sunday 29/09/2013 | 11:00-13:00

Paper Time: 11:24

Venue: Hall 3 (Level 0)

First Author: A.Souka EGYPT

Co Author(s):    S. Soliman              

Abstract Details

Purpose:

To document changes in intraocular pressure (IOP) and grade if iris neovascularization (NVI) in patients with neovascular glaucoma (NVG) after Intracameral bevacizumab injection as an anti-vascular endothelial growth factor (VEGF); the cause of new vessel formation.

Setting:

Faculty of Medicine, Alexandria Main University Hospital (iris photography and follow up) i-Care eye Hospital (intracameral injection)

Methods:

A retrospective review of eyes with NVG that were injected by single intracameral bevacizumab injection (2.5 mg/0.1ml), IOP measurements and NVI grading with Laatikainen Grading system were done and compared both preoperatively and post operatively.

Results:

12 eyes of 10 patients with NVG were injected. Eyes with pre-injection IOP ≤ 21 mmHg show stability throughout follow up period (3 months) while eyes with IOP > 21 mmHg showed a significant (p<0.0001) decrease in IOP. Regression of NVI was inversely proportional to pre-injection grade

Conclusions:

Intracameral bevacizumab can be used to control high IOP in NVG.

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