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Prevalence of age-related macular degeneration in an old French population (the MONTRACHET study)

Session Details

Session Title: AMD III

Session Date/Time: Sunday 29/09/2013 | 11:00-13:00

Paper Time: 11:40

Venue: Hall G1 (Level 2)

First Author: J.Ramel FRANCE

Co Author(s):    A. Muselier-Mathieu   B. Mathieu   C. Binquet   C. Tzourio     

Abstract Details

Purpose:

To report the prevalence of age-related macular degeneration (AMD) in a large population-based sample of French individuals older than 75 years.

Setting:

Department of Ophthalmology University Hospital, Dijon, France

Methods:

About 9000 individuals older than 65 were included in the 3C cohort study since 1999 from 3 French cities (Bordeaux, Dijon and Montpellier). In Dijon, an additional ophthalmic examination was performed 7 years after initial inclusion to assess the relation between systemic age-related degenerative and eye diseases in the MONTRACHET Study (Maculopathy. Optic Nerve. nuTRition. neurovAsCular and HEarT diseases). Every patient underwent a complete ophthalmic evaluation including color fundus pictures. Each photo was analyzed by 2 ophthalmologists. AMD was classified according to the international classification using size and number of drusen, presence of atrophic AMD and neovascular AMD (AREDS).

Results:

One thousand and thirty five subjects (385 men (37,2%) et 650 women (62,8%)) were included in the study. Mean age was 82.3 ± 3.8 years old. Prevalence of atrophic AMD was 7.4% (1.7% bilateral). There was no significative difference between men (7.6%) and women (7.3%) (p=0.90). Prevalence of neovascular AMD was 6.7% (1.0% bilateral) without difference between men and women (7.1% and 6.5% respectively, p=0.79). In 0.3% patients, we found an atrophic AMD in one eye and a neovascular AMD in the other eye.

Conclusions:

The first results on prevalence of AMD in this study are similar to those reported in the literature. These figures found after analysis of fundus photographies need to be compared to optical coherence tomography assessment. AMD is the most frequent macular disease in this class of age, with about one subject affected out of seven.

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