Session Title: Imaging II
Session Date/Time: Sunday 29/09/2013 | 08:00-10:00
Paper Time: 09:44
Venue: Hall G1 (Level 2)
First Author: S.Copete Piqueras SPAIN
Co Author(s): I. Flores J. Montero J. Ruiz Moreno
To assess the reproducibility of Spectral domain (SD-OCT) and Swept-source OCT (SS-OCT) in the study of choroidal thickness (CT) in healthy eyes.
Prospective, cross-sectional study developed in a single-center
We included 82 healthy eyes of 46 patients. Topcon 3D OCT 2000 and a 1050 nm SS-OCT prototype devices were used to perform OCT study using line protocol. Choroidal thickness was manually measured at Subfoveal location (SFCT) and every 500 µm to complete 3 mm temporally and nasaly to the fovea by two masked investigators. Mean macular choroidal thickness (MCT) was determined as the average of the thirteen choroidal thickness determinations.
SS-OCT determined SFCT in 100% of eyes vs. 74.4% with SD-OCT (p<0.05, Fisher's exact test). In those patients measured by both systems, mean SFCT was 279.4±96.9 μm (range, 84 to 506) with SD-OCT vs. 285.7±88.9 μm (range 130 to 527) with SS-OCT (p=0.11; Student’s t test paired data). Mean MCT was 242.2±81.8 μm (range 97.6 to 459) with SS-OCT vs. 243.8±78.8 μm (range 103.6 to 433.2) with SD-OCT (p=0.64; Student’s t test paired data). Difference in SFCT and MCT was not statistically significant between both devices. Intraclass interobserver and interdevice correlation coefficient (ICC) showed values higher than 0.9 for every location, being lightly better for SS-OCT than SD-OCT . SFCT Bland-Altman plots for SS-OCT and SD-OCT showed 95% of measurement between ±22 and ±34 μm respectively. Meanwhile it was 60 μm between devices.
SS-OCT permits SFCT determinations in more cases than SD-OCT. Although high correlation is observed, value comparison between different systems should be exercised with caution.