Session Title: Imaging II
Session Date/Time: Sunday 29/09/2013 | 08:00-10:00
Paper Time: 09:20
Venue: Hall G1 (Level 2)
First Author: I.Flores-Moreno SPAIN
Co Author(s): J. Ruiz-Medrano J. Montero J. Ruiz-Moreno
To correlate visual acuity in highly myopic eyes without macular disease with retinal and choroidal thickness as measured by spectral-domain optical coherence tomography (SD-OCT).
Castilla-La Mancha University (Spain)
60 eyes of 46 highly myopic patients (spherical equivalent ≥-6 diopters or axial length ≥ 26mm) were studied in a clinical setting. Eyes with any clinical evidence of maculopathy or amblyopia were excluded. Eyes were imaged using the 3D-2000 OCT (Topcon Corporation, Tokyo, Japan). Two independent investigators manually measured: choroidal thickness at 500µm intervals up to 2500µm nasal and temporal to the fovea, subfoveal choroidal thickness, foveal thickness, outer nuclear layer and photoreceptors in addition to retinal pigment epithelium (RPE). Statistical analysis was performed.
Mean age was 45.9±17.9 years (range, 18 to 99), mean best-corrected visual acuity (BCVA) LogMAR was 0.11±0.19 (range, 0 to 1), mean axial length 28.2±2.4 mm (range, 26 to 35.3), and mean spherical equivalent was -12.05±5.02 D (range, -6 to -26). Mean macular choroidal thickness was 157±84.6 m (range, 16.7 to 426.5), mean subfoveal choroidal thickness was 166±88.7 m (range, 13.5 to 486.5), mean foveal thickness was 221.1±30.3 m (range, 157.5 to 296), mean outer nuclear layer was 121.3±22.6 m (range, 74 to 191.5) and mean photoreceptors in addition to RPE was 99.5±10.8 m (range, 71.5 to 115.5). BCVA (LogMAR) negative correlated with macular choroidal thickness (r=-0.371; p=0.003), subfoveal choroidal thickness (r=-0.358; p=0.004) and photoreceptors and RPE aggregate (r=-0.346; p=0.006).
Subfoveal choroidal thickness, mean macular choroidal thickness and outer retinal thickness are the most important predictive factors of visual acuity in highly myopic eyes without macular pathology.